Cristiano Ronaldo will not play today. He did not travel to Tashkent.
Coach Ange Postecoglou rested him. There is no injury behind the call.
Kingsley Coman and Mohamed Simakan were also left out of the squad.
Postecoglou said the pressure of matches and the amount of travel forced his hand.
Ronaldo scored three goals in the 5-3 win over Al Kholood on Thursday.
The hat trick took him to 985. He is 15 short of 1,000 career goals.
Ronaldo has nine goals in 12 club appearances this season, Sportstar reports.
Joao Felix and Sadio Mane will lead the attack. Felix gave four assists on Thursday.
Pakhtakor have lost just one of their last 13 home games.
Al Nassr are ninth in the West group. The top eight reach the knockout stage.
Sports Mole predicts a 1-1 draw, with Pakhtakor hard to beat at home.
Read the full explainer: why Ronaldo is out, who plays, and what happens next.
Get the full breakdown, key numbers, and what happens next.
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