Perth Glory lead Adelaide United 2-0 early in their Round 3 clash at HBF Park in Perth.
Perth scored twice inside the first 20 minutes, according to live score data on Sunday.
Adelaide lost 2-0 to Lion City Sailors on Thursday in the AFC Champions League Two.
Coach Airton Andrioli backed his young players to bounce back in Perth on Sunday.
We are disappointed with Thursday, but we must focus on the next game, Andrioli said.
Perth named a 4-4-2 with Pieter Jacobsz and Tom Lawrence leading the attack.
Adelaide lined up 4-3-3 with Brody Burkitt, Amlani Tatu and Jonny Yull up front.
Adelaide have 19 wins over Perth, who have 15, with 12 draws in 46 meetings.
About 6,000 fans were expected at HBF Park, which can hold 20,500 people.
Adelaide face three games in a short window, then travel to Singapore for Asian action.
Perth host the Newcastle Jets at HBF Park on November 7 in their next A-League game.
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